What role might H. pylori infection play in other diseases?

Last Updated:

H. pylori infection is associated with a higher risk of hypertension, nonalcoholic fatty liver disease, subclinical atherosclerosis, and, potentially, irritable bowel syndrome.

People with H. pylori infections are more likely to have or develop hypertension, non-alcoholic fatty liver disease, and subclinical atherosclerosis. H. pylori infection may also increase the risk of developing irritable bowel syndrome (IBS), but more research is needed to confirm this association.[1][2][3][4][5]

H. pylori treatment may help to reduce IBS symptoms and is also associated with a reduced risk of gastric cancer. Some research shows that eradication therapy could increase the risk of developing gastroesophageal reflux disease, but other research suggests it has no effect.[5][6]

References
2.^Heydari K, Yousefi M, Alizadeh-Navaei R, Lotfi P, Sheydaee F, Raei M, Vahdatinia A, Hessami A, Rafati S, Moosazadeh M, Ghasemian R, Salehi F, Massoudi H, Ghaffari-Saravi F, Rismantab SHelicobacter pylori Infection and Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.Turk J Gastroenterol.(2022-03)
4.^Chenyu Li, Yujun Shuai, Xiaodong Zhou, Hongxia ChenAssociation between Helicobacter pylori infection and irritable bowel syndrome: A systematic review and meta-analysisMedicine (Baltimore).(2020 Dec 11)