What are some risk factors for osteopenia?

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There are many factors, both modifiable and non-modifiable, that may increase the risk of osteopenia, including:[1][2][3]

  • Family history of osteopenia and/or osteoporosis
  • White or Asian race
  • Advancing age
  • BMI <18.5 kg/m2
  • Sedentary lifestyle
  • Lower socioeconomic status
  • Lower levels of education
  • Alcohol use disorder
  • Early onset menopause
  • Cigarette smoking
  • Certain medical conditions (e.g., hyperthyroidism, hyperparathyroidism, anorexia, chronic kidney disease, HIV)
  • Certain medications (e.g., glucocorticoids, proton pump inhibitors, anticonvulsants)
  • Chronic nutritional deficiencies (e.g., calcium, vitamin D)
References
2.^Karaguzel G, Holick MFDiagnosis and treatment of osteopenia.Rev Endocr Metab Disord.(2010-Dec)
3.^Varacallo M, Seaman TJ, Jandu JS, Pizzutillo POsteopeniaStatPearls.(2022-10)