What are the risk factors for developing psoriatic arthritis?

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Although it isn’t easy to predict whether patients with psoriasis will develop psoriatic arthritis, some potential risk factors have been identified, including:[1]

  • Corticosteroid use within 2 years of first developing psoriasis
  • Pregnancy within 2 years prior to psoriasis onset[2]
  • Trauma that required medical care[3]
  • Vaccination against rubella[3]
  • Smoking
  • Infections requiring hospitalization
  • Heavy drinking
  • Family history of psoriatic arthritis
  • Obesity

It is important to note that the above risk-associations were mostly found through case-control (observational) studies, so it isn’t yet clear whether they play a causative role in developing the disease.

References
2.^Thumboo J, Uramoto K, Shbeeb MI, O'Fallon WM, Crowson CS, Gibson LE, Michet CJ, Gabriel SERisk factors for the development of psoriatic arthritis: a population based nested case control study.J Rheumatol.(2002-Apr)
3.^Pattison E, Harrison BJ, Griffiths CE, Silman AJ, Bruce INEnvironmental risk factors for the development of psoriatic arthritis: results from a case-control study.Ann Rheum Dis.(2008-May)