Can people with systemic lupus erythematosus use hormonal contraceptives?
People with systemic lupus erythematosus can use hormonal contraceptives, but it is crucial to consult a medical provider due to potential risks associated with estrogen exposure, especially for those with antiphospholipid antibodies or high disease activity. In these cases, alternative contraception methods, such as long-acting reversible contraceptives, may be safer.
Last Updated:May 16, 2025
Yes,[1] but it is important to work closely with a medical provider when considering hormonal contraceptives, as the estrogen exposure from birth control pills can be too risky for certain people with SLE — specifically those with antiphospholipid antibodies and/or high SLE disease activity. In such cases, alternative methods of contraception, like long-acting reversible contraceptives (e.g., intrauterine devices), may be a safer option.[2]