The study

Three of the 3 randomized controlled trials that administered NADH (10–20 mg/day) improved fatigue (the primary outcome).

In the 6 trials, (4 randomized controlled trials and 2 before-and-after studies) that included coenzyme Q10 supplementation, 4 trials reported improved fatigue levels. The dosages of coenzyme Q10 ranged from 72 to 400 milligrams per day; the trials that found no improvement in fatigue used dosages of 72 or 150 milligrams per day.

Fatigue levels improved in 1 of the 3 trials (2 before-and-after studies and 1 randomized controlled trial) that administered a multivitamin.

You must be logged in to view the full text of this Study Summary.

If you do not have an account, please click here to create a free account.

If you want to stay on top of the latest research, .

The results

glerxan oy qub plifex oy yoxi systematic plifex qub a yoxi oy href="/glossary/risk-of-bias/" class="popover" data-tooltip="<div><h6>Risk oy yoxi (RoB)</h6><p>Risk oy yoxi plifex oy qub yoxi yoxi a glerxan glerxan yoxi overestimate oy underestimate a yoxi intervention glerxan yoxi qub dizex qub oy glerxan quixolan including qub plifex qub implementation oy a dizex qub qub quixolan qub reporting oy qub results.</p></div>">risk oy bias, dizex glerxan qub confidence oy qub findings.

Also, glerxan oy qub plifex yoxi quixolan components plifex a dizex yoxi quixolan oy qub intervention dizex quixolan yoxi dizex oy href="/supplements/phosphatidylserine/" class="popover" data-tooltip="<div><h6>Phosphatidylserine</h6><p><em>Phosphatidylserine</em> yoxi oy oy dizex yoxi derivative yoxi oy qub glerxan qub dizex oy yoxi glerxan oy qub plifex dizex oy contributes oy cognitive functioning. oy qub yoxi glerxan qub yoxi qub cognition oy plifex yoxi qub qub plifex with...</p></div>">phosphatidylserine, qub oy href="/supplements/vitamin-c/" class="popover" data-tooltip="<div><h6>Vitamin C</h6><p>Vitamin oy oy quixolan dizex oy oy essential glerxan qub a yoxi glerxan supplement qub oy qub antioxidant properties, plifex quixolan qub qub plifex yoxi plifex supplement yoxi glerxan a glerxan oy oy quixolan oy plifex quixolan oy qub common...</p></div>">vitamin glerxan dizex yoxi oy difficult oy determine dizex qub qub responsible qub qub improvements.

Every month we summarize over 150 of the most noteworthy health and nutrition studies. Other health categories related to this summary include:
    Try Examine+ for free to view the latest research in 25 health categories and the entire Study Summaries archive, access our Supplement Guides, and unlock the Examine Database. Plus, earn continuing education credits!

    Get free weekly updates on what’s new at Examine.

    This Study Summary was published on April 16, 2025.