Anthocyanins may reduce inflammation in older adults with higher dementia risk Original paper
In this 24-week randomized controlled trial in 99 older adults, supplementing daily with anthocyanins — antioxidants found in berries and colorful fruits — lowered inflammation levels and improved biomarkers of cardiovascular health.
This Study Summary was published on June 4, 2025.
The study
The trial recruited older adults (ages 60–80) with mild cognitive impairment or at least 2 cardiometabolic conditions that are known to increase the risk of dementia. The participants took 320 mg per day of anthocyanins or a placebo.
Anthocyanin treatment reduced several biomarkers of inflammation (e.g., CRP and interleukin 6), lowered LDL cholesterol levels, and improved cardiometabolic scores (based on a composite of blood lipids and glucose levels). The benefits of anthocyanins were greater in participants with higher baseline inflammation levels.
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The results
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This Study Summary was published on June 4, 2025.