Can Atlas pistachio oil improve knee osteoarthritis symptoms? Original paper

In this 4-week randomized controlled trial in 92 older adults with knee osteoarthritis, rubbing the knee with Atlas pistachio oil, compared to diclofenac gel, resulted in greater pain reduction.

This Study Summary was published on March 28, 2025.

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The study

The participants were assigned to rub their knee with a fingertip amount of either Atlas pistachio oil (derived from Pistacia atlantica trees in Iran; a relative of the common pistachio) or diclofenac gel (the control) 3 times daily.

Osteoarthritis symptoms improved in both groups, but pain improved more in the Atlas pistachio group, according to scores on a Visual Analog Scale and the Knee Injury and Osteoarthritis Outcome Score.

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The results

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    This Study Summary was published on March 28, 2025.