E-cigarettes may aid in smoking cessation in high-risk groups Original paper

In this randomized controlled trial in 1,246 participants who smoked, adding e-cigarettes to standard tobacco smoking cessation counseling increased abstinence rates at 6 months in participants with psychiatric conditions and/or substance use issues, compared to counseling alone.

This Study Summary was published on April 2, 2025.

The study

In this multicenter trial, the participants were randomized to 1 of 2 groups:

  • Intervention: Standard counseling plus 2 e-cigarette starter kits and free e-liquids
  • Control: Standard counseling plus a cash voucher that could be spent on anything, including nicotine replacement therapy

Abstinence from tobacco smoking was assessed by measuring anabasine (a biomarker that distinguishes active tobacco use from nicotine replacement therapy) in urine samples.

  • In the participants with psychiatric conditions, smoking abstinence was 30.8% in the intervention group versus 14.8% in the control group.
  • In the participants with substance use issues, abstinence was 29.0% in the intervention group versus 18.9% in the control group.
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The results

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    This Study Summary was published on April 2, 2025.