The study

A total of 552 participants with cystic fibrosis were included in this review, and most studies focused on children. The treatment duration of the included studies ranged from 1 month to 12 months. Probiotics were given in 9 studies, and synbiotics were given in 4 studies, mainly from Lactobacillus and/or Bifidobacterium genera.

According to the meta-analysis, taking either probiotics or synbiotics had no effect on lung function or pulmonary exacerbations (periods of worsening respiratory symptoms).

A majority of the trials had an unclear risk of bias.

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The results

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    This Study Summary was published on June 12, 2025.