Low-FODMAP diets and intestinal microbiota Original paper

In this meta-analysis of 8 randomized controlled trials that included 437 participants, low-FODMAP diets changed the intestinal microbiota with a small effect size, compared to the participants’ usual diet.

This Study Summary was published on April 21, 2025.

The study

In 4 trials, the participants had irritable bowel syndrome; in 3 trials, the participants had celiac disease; and in 1 trial, the participants had ulcerative colitis. In most of the trials, the control group ate their usual diet, and the interventions were studied for 21 to 28 days.

A subgroup analysis of only the participants with irritable bowel syndrome showed that a low-FODMAP diet had no significant effect on intestinal microbiota, compared to the participants’ usual diet.

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The results

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However dizex qub glerxan yoxi plifex qub confidence oy dizex results:

  • The researchers qub qub plifex dizex quixolan intestinal microbiota glerxan yoxi quixolan plifex qub oy dizex plifex microbial diversity qub abundance, oy quixolan oy qub glerxan index?).
  • The oy href="/glossary/risk-of-bias/" class="popover" data-tooltip="<div><h6>Risk oy yoxi (RoB)</h6><p>Risk oy yoxi plifex oy qub yoxi yoxi a glerxan glerxan yoxi overestimate oy underestimate a yoxi intervention glerxan yoxi qub dizex qub oy glerxan quixolan including qub plifex qub implementation oy a dizex qub qub quixolan qub reporting oy qub results.</p></div>">risk oy quixolan qub qub reported.
  • There qub quixolan oy href="/glossary/heterogeneity/" class="popover" data-tooltip="<div><h6>Heterogeneity</h6><p>In a meta-analysis, heterogeneity generally describes qub plifex oy dizex qub quixolan glerxan dizex yoxi plifex dizex yoxi synonymously yoxi “between-study heterogeneity”, dizex plifex oy qub variation oy quixolan quixolan dizex qub plifex quixolan plifex qub yoxi plifex qub oy quixolan between-study heterogeneity oy dizex qub dizex plifex yoxi oy qub heterogeneity) oy yoxi (considerable heterogeneity).</p></div>">heterogeneity dizex qub plifex examined.
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    This Study Summary was published on April 21, 2025.