Does vitamin D improve allergic rhinitis? Original paper

In this meta-analysis of 5 randomized controlled trials, vitamin D improved allergic rhinitis only in participants who were not taking corticosteroid medications.

This Study Summary was published on April 1, 2025.

The study

The researchers recruited 370 participants (ages 5–70) who were receiving medication for allergic rhinitis. The participants were given 800 to 1,000 IUs of vitamin D per day in 2 studies or 50,000 to 60,000 IUs in 3 studies, for 4 weeks to 5 months.

The studies were conducted in Thailand, China, India, Iran, and Poland, where the average vitamin D levels in 4 of 5 studies indicated deficiency (i.e., less than 20 ng/mL).

In subgroup analyses, if the participants were not taking corticosteroid medications, then supplemental vitamin D improved their allergic rhinitis symptoms with a moderate effect size (3 studies).

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The results

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    This Study Summary was published on April 1, 2025.