L-arginine and vitamin C for managing COPD-related symptoms Original paper

In this randomized controlled trial in 150 older adults with stable chronic obstructive pulmonary disorder (COPD), supplementation with L-arginine and vitamin C improved self-reported shortness of breath and ability to perform activities of daily living.

This Study Summary was published on June 3, 2025.

The study

The participants in the intervention group took 1.66 grams of L-arginine and 500 mg of liposomal (highly bioavailable) vitamin C twice daily for 4 weeks.

The researchers assessed COPD-related symptoms, ability to perform activities of daily living, and lung function with validated questionnaires and clinical tests. Compared to a placebo, supplementation with L-arginine and vitamin C improved self-reported shortness of breath, quality of life, and ability to perform activities of daily living. There were no differences in the 6-minute walk test or vital capacity lung test between the intervention group and the control group.

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The results

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    This Study Summary was published on June 3, 2025.