Can eating cruciferous vegetables help with H. pylori infection? Original paper

The 8 included clinical trials examined the effect of sulforaphane on H. pylori infection. Sulforphane was consumed as broccoli sprouts (6 studies), broccoli seed extract (1 study), or broccoli tips (1 study).

The researchers examined the effect of sulforaphane as the main treatment in 5 studies and the effect of sulforaphane added to standard treatment (a proton pump inhibitor and 2 antibiotics) in 3 studies.

None of the studies reported a clear effect of sulforaphane on markers of H. pylori colonization, compared with a control group. However, several studies were limited by very small sample sizes.

The authors of the systematic review described several studies as showing that sulforaphane had an effect of on H. pylori, but this was based on reductions in H. pylori over time (which could be explained by factors other than sulforaphane) and/or nonsignificant changes.