Cataracts

Last Updated: July 25, 2023

A cataract is a clouding of one or both lenses of the eye that can cause blurry vision, glare, poor night vision, double vision, and seeing colors that seem faded. Cataracts are a leading cause of blindness.

Cataracts falls under theEyes & Visioncategory.

What are cataracts?

Cataracts are cloudy areas on the lens of the eye that lead to visual disturbances. If untreated, they can ultimately result in blindness.

What are the main signs and symptoms of cataracts?

The main signs and symptoms of cataracts include blurred vision, poor night vision, difficulty distinguishing colors, halos around lights, double vision, and light sensitivity. These visual disturbances worsen as the cataract develops.

How are cataracts diagnosed?

Cataracts are diagnosed through an eye examination conducted by an ophthalmologist, who dilates the pupil and uses a slit-lamp microscope to examine the lens and the back of the eye. Although symptoms can aid in diagnosis, they may also indicate other eye conditions like glaucoma.

What are some of the main medical treatments for cataracts?

The main medical treatment for cataracts is surgery, during which the cloudy lens is removed and replaced with an artificial intraocular lens chosen by the surgeon. This procedure can also correct refractive errors that may have required corrective lenses.

Have any supplements been studied for cataracts?

Some evidence suggests that caffeine may help prevent and treat cataracts, and higher coffee intake is associated with lower risk. Although vitamins E and C and beta carotene have been studied for their antioxidant properties, the evidence does not currently support their use in cataract treatment, though vitamin B12 may have a role in prevention.

How could diet affect cataracts?

A higher intake of fruits and vegetables is associated with a reduced risk of developing cataracts. Additionally, vegetarian or vegan diets may lower this risk, potentially due to increased consumption of vegetables and legumes.

Are there any other treatments for cataracts?

Research is ongoing into new medical treatments for cataracts, including antioxidants like N-acetylcysteine and oxysterols such as lanosterol, which may help reduce oxidation and stabilize lens proteins. However, there is still uncertainty regarding the effective dosages and the delivery of these treatments through topical methods like eye drops.

What causes cataracts?

Cataracts are caused by proteins that clump together in the lens, which leads to cloudiness and discoloration that disrupts light filtration and vision. The primary cause is aging, particularly in people over age 60, and additional risk factors include genetics, smoking, diabetes, sun damage, and eye trauma.

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References
  1. ^Cataract(MedlinePlus)
  2. ^(National Eye Institute)
  3. ^What are cataracts?(American Academy of Ophthalmology)
  4. ^Zhang JH, Ramke J, Lee CN, Gordon I, Safi S, Lingham G, Evans JR, Keel SA Systematic Review of Clinical Practice Guidelines for Cataract: Evidence to Support the Development of the WHO Package of Eye Care Interventions.Vision (Basel).(2022-Jun-20)
  5. ^Cataract in the Adult Eye Preferred Practice Pattern(2016)
  6. ^Varma SDEffect of coffee (caffeine) against human cataract blindness.Clin Ophthalmol.(2016)
  7. ^Kronschläger M, Ruiß M, Dechat T, Findl OSingle high-dose peroral caffeine intake inhibits ultraviolet radiation-induced apoptosis in human lens epithelial cells in vitro.Acta Ophthalmol.(2021-Jun)
  8. ^Glaser TS, Doss LE, Shih G, Nigam D, Sperduto RD, Ferris FL, Agrón E, Clemons TE, Chew EY,The Association of Dietary Lutein plus Zeaxanthin and B Vitamins with Cataracts in the Age-Related Eye Disease Study: AREDS Report No. 37.Ophthalmology.(2015-Jul)
  9. ^Mathew MC, Ervin AM, Tao J, Davis RMAntioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract.Cochrane Database Syst Rev.(2012-Jun-13)
  10. ^Appleby PN, Allen NE, Key TJDiet, vegetarianism, and cataract risk.Am J Clin Nutr.(2011-May)
  11. ^Tina H T Chiu, Chia-Chen Chang, Chin-Lon Lin, Ming-Nan LinA Vegetarian Diet Is Associated with a Lower Risk of Cataract, Particularly Among Individuals with Overweight: A Prospective StudyJ Acad Nutr Diet.(2020 Dec 11)
  12. ^Fan H, Han X, Shang X, Zhu Z, He M, Xu G, Chen Z, Deng RFruit and vegetable intake and the risk of cataract: insights from the UK Biobank study.Eye (Lond).(2023-Mar-27)
  13. ^Lee BJ, Afshari NAAdvances in drug therapy and delivery for cataract treatment.Curr Opin Ophthalmol.(2023-Jan-01)
  14. ^Xu J, Fu Q, Chen X, Yao KAdvances in pharmacotherapy of cataracts.Ann Transl Med.(2020-Nov)
  15. ^National Eye Institute(January 2023)
Examine Database References
  1. Cataract Risk - Christen WG, Glynn RJ, Sesso HD, Kurth T, MacFadyen J, Bubes V, Buring JE, Manson JE, Gaziano JMAge-related cataract in a randomized trial of vitamins E and C in menArch Ophthalmol.(2010 Nov)
  2. Cataract Risk - McNeil JJ, Robman L, Tikellis G, Sinclair MI, McCarty CA, Taylor HRVitamin E supplementation and cataract: randomized controlled trialOphthalmology.(2004 Jan)