Ehlers-Danlos syndrome (EDS) is a group of genetic disorders caused by faulty collagen synthesis; it affects the connective tissues and leads to symptoms such as overly elastic skin, joint hypermobility, and fragile blood vessels. In 2017, 13 variants of EDS were classified, and 12 had distinct genetic characteristics.

Ehlers-Danlos syndrome (EDS) has various signs and symptoms depending on the type; hypermobile EDS (hEDS) is characterized by overly flexible joints, stretchy skin, and excessive bruising. It can lead to secondary complications like chronic pain, dysautonomia, and anxiety, and serious complications may occur in vascular and kyphoscoliotic EDS, necessitating regular monitoring.

Ehlers-Danlos syndrome (EDS) is typically suspected based on clinical signs like skin hyperextensibility and shoulder dislocation, though many milder cases may remain undiagnosed. Diagnosis can be confirmed through genetic testing, although the most common type, hypermobile EDS, lacks a known genetic cause.

There is no cure for Ehlers-Danlos syndrome (EDS); treatment focuses on managing symptoms and preventing damage and often involves pain medications and supportive devices. Regular monitoring by specialists and preventative measures for cardiovascular complications are also recommended.

Dietary supplements have not been formally studied for Ehlers-Danlos syndrome (EDS), but they may be recommended to address nutritional deficiencies and manage symptoms. For instance, vitamin D is often suggested due to its association with hypermobile EDS, and other supplements like vitamin C, glucosamine, carnitine, and coenzyme Q10 have been used anecdotally for various symptoms.

People with hypermobile Ehlers-Danlos syndrome (hEDS) often experience gastrointestinal issues that can lead to poor nutrient intake and unintended weight loss. Dietary changes, like adopting a low-FODMAP diet and increasing soluble fiber, may help alleviate these GI symptoms.

Treatment for Ehlers-Danlos syndrome (EDS) focuses on preventing complications through physical and occupational therapy, along with regular moderate exercise. These approaches aim to prevent joint dislocations, preserve joint function, reduce chronic pain, and slow the onset of osteoarthritis.

Ehlers-Danlos syndrome (EDS) is caused by inherited gene mutations that affect collagen processing and synthesis, and leads to various EDS variants with distinct symptoms. These mutations can result in significant vulnerability of body organs and an increased risk of injury from normal activities.