Psoriasis

Last Updated: October 13, 2024

Psoriasis is a chronic skin disease that causes patches of thick, red, scaly skin on various parts of the body. Its cause is unknown and symptoms tend to wax and wane over time.

Psoriasis falls under theSkin, Hair, & Nailscategory.

What is psoriasis?

Psoriasis is a chronic inflammatory skin disease characterized by the rapid regeneration of skin cells, which leads to thick, red patches covered with white or silver scales. A 2017 study indicated that up to 11% of adults and 1.4% of children globally are affected by this condition.

What are the main signs and symptoms of psoriasis?

Psoriasis is characterized by elevated red lesions that are dry and covered with silvery scales. These lesions can occur on various parts of the body, including the elbows, knees, scalp, face, palms, and feet.

How is psoriasis diagnosed?

Psoriasis is diagnosed primarily through a clinical evaluation of the rash, symptoms, and ruling out of other similar conditions by healthcare professionals. This process includes obtaining a clinical history and conducting a thorough skin examination.

What are some of the main medical treatments for psoriasis?

Medical treatments for psoriasis vary based on the severity of symptoms and include topical creams, oral or injected immunosuppressants, and phototherapy. Topical treatments are typically used for milder cases, but more severe cases may require immunosuppressants or phototherapy if topical treatments are ineffective.

Have any supplements been studied for psoriasis?

Several dietary supplements (including fish oil, vitamin D, selenium, and probiotics) have been studied for their potential effects on psoriasis symptoms; some showed benefits, whereas others were deemed ineffective. However, more rigorous research is necessary before definitive recommendations can be established.

How could diet affect prostate psoriasis?

Diet can affect psoriasis because studies show that individuals with psoriasis often consume fewer Mediterranean diet foods. Dietary interventions, such as a hypocaloric or gluten-free diet, may help reduce psoriasis symptoms, but dietary changes should complement standard medical treatments.

Are there any other treatments for psoriasis?

There is weak evidence that saltwater baths combined with phototherapy may be effective for psoriasis, but further research is needed. Additionally, small studies suggest that meditation might help alleviate some symptoms.

What causes psoriasis?

Psoriasis is believed to be caused by an excessive immune response that leads to an overproduction of skin cells. Its development involves a combination of genetic, environmental, and psychological factors.

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References
  1. ^The content of this page was partially adapted from MedlinePlus of the National Library of Medicine
  2. ^I M Michalek, B Loring, S M JohnA systematic review of worldwide epidemiology of psoriasisJ Eur Acad Dermatol Venereol.(2017 Feb)
  3. ^April W Armstrong, Charlotte ReadPathophysiology, Clinical Presentation, and Treatment of Psoriasis: A ReviewJAMA.(2020 May 19)
  4. ^Naoko Kanda, Toshihiko Hoashi, Hidehisa SaekiNutrition and PsoriasisInt J Mol Sci.(2020 Jul 29)
  5. ^Céline Phan, Mathilde Touvier, Emmanuelle Kesse-Guyot, Moufidath Adjibade, Serge Hercberg, Pierre Wolkenstein, Olivier Chosidow, Khaled Ezzedine, Emilie SbidianAssociation Between Mediterranean Anti-inflammatory Dietary Profile and Severity of Psoriasis: Results From the NutriNet-Santé CohortJAMA Dermatol.(2018 Sep 1)
  6. ^Luigi Barrea, Nicola Balato, Carolina Di Somma, Paolo Emidio Macchia, Maddalena Napolitano, Maria Cristina Savanelli, Katherine Esposito, Annamaria Colao, Silvia SavastanoNutrition and psoriasis: is there any association between the severity of the disease and adherence to the Mediterranean diet?J Transl Med.(2015 Jan 27)
  7. ^Adam R Ford, Michael Siegel, Jerry Bagel, Kelly M Cordoro, Amit Garg, Alice Gottlieb, Lawrence J Green, Johann E Gudjonsson, John Koo, Mark Lebwohl, Wilson Liao, Arthur M Mandelin 2nd, Joseph A Markenson, Nehal Mehta, Joseph F Merola, Ronald Prussick, Caitriona Ryan, Sergio Schwartzman, Evan L Siegel, Abby S Van Voorhees, Jashin J Wu, April W ArmstrongDietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic ReviewJAMA Dermatol.(2018 Aug 1)
  8. ^Frank Peinemann, Marco Harari, Sandra Peternel, Thalia Chan, David Chan, Alexander M Labeit, Thilo GambichlerIndoor salt water baths followed by artificial ultraviolet B light for chronic plaque psoriasisCochrane Database Syst Rev.(2020 May 5)
  9. ^A Caresse Gamret, Alexandra Price, Raymond M Fertig, Hadar Lev-Tov, Anna J NicholsComplementary and Alternative Medicine Therapies for Psoriasis: A Systematic ReviewJAMA Dermatol.(2018 Nov 1)
  10. ^David Boothe W, Tarbox JA, Tarbox MBAtopic Dermatitis: Pathophysiology.Adv Exp Med Biol.(2017)
  11. ^Reynolds KA, Pithadia DJ, Lee EB, Liao W, Wu JJA systematic review of treatment strategies for erythrodermic psoriasis.J Dermatolog Treat.(2021-Feb)
  12. ^Ritchlin CT, Colbert RA, Gladman DDPsoriatic Arthritis.N Engl J Med.(2017-03-09)
Examine Database References
  1. Psoriasis Symptoms - Allan SJ, Kavanagh GM, Herd RM, Savin JAThe effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trialBr J Dermatol.(2004 May)
  2. Psoriasis Symptoms - Padilla HC, Laínez H, Pacheco JAA new agent (hydrophilic fraction of polypodium leucotomos) for management of psoriasisInt J Dermatol.(1974 Sep-Oct)
  3. Psoriasis Symptoms - Sadeghian G, Ziaei H, Nilforoushzadeh MATreatment of localized psoriasis with a topical formulation of zinc pyrithioneActa Dermatovenerol Alp Panonica Adriat.(2011)
  4. Psoriasis Symptoms - Gok Metin Z, Helvaci A, Gulbahar Eren MEffects of Aloe vera in adults with mucocutaneous problems: A systematic review and meta-analysis.J Adv Nurs.(2021-Mar)
  5. Psoriasis Symptoms - Zhu Y, Xu F, Chen H, Zheng QThe efficacy and safety of probiotics in the adjuvant treatment of psoriasis: a systematic review and meta-analysis of randomized controlled trials.Front Med (Lausanne).(2024 Sep 4)
  6. Total cholesterol - Morken T, Bohov P, Skorve J, Ulvik R, Aukrust P, Berge RK, Livden JKAnti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis--a pilot studyScand J Clin Lab Invest.(2011 Jul)