Traumatic Brain Injury

Last Updated: October 13, 2024

Traumatic Brain Injury (TBI) is damage to the brain caused by a sudden injury - like a bump, blow, or jolt.

Traumatic Brain Injury falls under theBrain Healthcategory.

What is traumatic brain injury?

Traumatic brain injury (TBI) is a disruption in brain function caused by physical trauma and is classified as either closed or open based on whether the skull is penetrated. TBIs are further categorized as mild, moderate, or severe. Mild TBI is commonly known as a concussion, and severe cases can lead to coma, permanent disability, or death.

What are the main signs and symptoms of traumatic brain injury?

Mild traumatic brain injury (TBI) can cause symptoms such as headache, nausea, fatigue, and memory issues, whereas moderate to severe TBI may occur with worsening symptoms like persistent headaches, severe vomiting, confusion, and seizures. Both mild and severe TBIs can initially appear similar, but the symptoms may escalate over time.

How is traumatic brain injury diagnosed?

Traumatic brain injury is diagnosed via a thorough medical history and neurological examination that looks for signs such as decreased consciousness, confusion, amnesia, and neurological deficits. Imaging tests like CT or MRI may also be performed to identify any serious brain injuries that need surgical intervention.

What are some of the main medical treatments for traumatic brain injury?

Mild traumatic brain injury (TBI) is typically treated with monitoring and strategies for returning to daily activities, whereas moderate to severe cases require emergency neurological life support and may involve surgery to relieve pressure on the brain. Once stable, people with TBI may also receive noninvasive treatments like osmotic therapy to manage pressure.

Have any supplements been studied for traumatic brain injury?

Supplemental vitamin E and C may have positive effects on traumatic brain injury, and curcumin, DHA, vitamin D, and magnesium also show potential benefits, though further research is needed to determine the optimal dosages and timing for these supplements.

How could diet affect traumatic brain injury?

Although there are no specific dietary strategies that are proven to improve recovery from traumatic brain injury (TBI), maintaining a normal BMI and consuming a diet rich in micronutrients may be beneficial. Being underweight can negatively affect recovery outcomes, although this effect is not exclusive to TBI.

Are there any other treatments for traumatic brain injury?

Several new treatments for traumatic brain injury (TBI) are being researched — including statins, progesterone, cyclosporin A, targeted temperature management, hyperbaric oxygen therapy, and erythropoietin — and each shows potential neuroprotective effects. Additionally, long-term interventions such as cognitive behavioral therapy, balance training, and vestibular therapy may be necessary to address persistent functional impairments.

What causes traumatic brain injury?

Traumatic brain injury (TBI) is caused by an external force that impacts the head, which leads to brain injury. In people over age 65, falls are the most common cause, whereas younger people often experience TBIs from motor vehicle accidents, sports injuries, and interpersonal violence.

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References
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Examine Database References
  1. Brain Injury Symptoms - Ata Mahmoodpoor, Ghaffar Shokouhi, Hadi Hamishehkar, Hassan Soleimanpour, Sarvin Sanaie, Jahan Porhomayon, Fatemeh Rasouli, Nader D NaderA pilot trial of l-carnitine in patients with traumatic brain injury: Effects on biomarkers of injuryJ Crit Care.(2018 Jun)
  2. Fatigue Symptoms - P P Kalinskiĭ, V V Nazarov[Use of phenotropil in the treatment of asthenic syndrome and autonomic disturbances in the acute period of mild cranial brain trauma]Zh Nevrol Psikhiatr Im S S Korsakova.(2007)
  3. Fatigue Symptoms - George Sakellaris, George Nasis, Maria Kotsiou, Maria Tamiolaki, Giorgos Charissis, Athanasios EvangeliouPrevention of traumatic headache, dizziness and fatigue with creatine administration. A pilot studyActa Paediatr.(2008 Jan)
  4. Memory - McLean A Jr, Cardenas DD, Burgess D, Gamzu EPlacebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxiaBrain Inj.(1991 Oct-Dec)
  5. Insomnia Signs and Symptoms - Malarkey ME, Fu AJ, Mannan N, Shaw OM, Haight TJ, Cota MR, Jahed NC, Werner JK, Brody DLInternet-Guided Cognitive Behavioral Therapy for Insomnia Among Patients With Traumatic Brain Injury: A Randomized Clinical Trial.JAMA Netw Open.(2024 Jul 1)
  6. Inflammation - Masbough F, Kouchek M, Koosha M, Salarian S, Miri M, Raoufi M, Taherpour N, Amniati S, Sistanizad MInvestigating the Effect of High-Dose Vitamin D3 Administration on Inflammatory Biomarkers in Patients with Moderate to Severe Traumatic Brain Injury: A Randomized Clinical Trial.Iran J Med Sci.(2024 Oct)