Vulvovaginal Candidiasis (Yeast Infection)

Last Updated: October 13, 2024

Vulvovaginal candidiasis (VVC) is a common vaginal infection caused by species of Candida yeast. These are normal inhabitants of the vaginal microbiome, but certain contraceptives, conditions, and behaviors can disrupt the vaginal environment and lead to an overgrowth.

Vulvovaginal Candidiasis (Yeast Infection) falls under theWomen’s Healthcategory.

What is vulvovaginal candidiasis?

Vulvovaginal candidiasis (VVC), commonly known as a yeast infection, is a prevalent vaginal fungal infection caused by the overgrowth of Candida species, primarily C. albicans. Although most people experience mild-to-moderate, uncomplicated VVC, some may suffer from complicated VVC, which involves severe, recurrent infections in those with underlying health issues.

What are the main signs and symptoms of VVC?

The main sign of vulvovaginal candidiasis (VVC; yeast infection) is an abnormal discharge that may be thick or watery and resembles cottage cheese, without a strong odor and with normal vaginal pH. Symptoms can include itching, irritation, soreness, redness, swelling, and burning sensations, although VVC can also occur without symptoms.

How is VVC diagnosed?

Vulvovaginal candidiasis (VVC; yeast infection) is diagnosed through a medical examination and microscopic analysis of vaginal discharge to identify the presence of Candida. If Candida is not detected, a culture may be performed to promote growth for further observation.

What are some of the main medical treatments for VVC?

The main medical treatments for vulvovaginal candidiasis (yeast infection) are antifungal drugs, which alter the permeability of the fungal cell membrane. Both oral and topical antifungals are effective, and topical options are more effective at reducing Candida colonization and are available over the counter, whereas prescription antifungals may be necessary for infections caused by non-Candida albicans species.

Have any supplements been studied for VVC?

Certain probiotic strains and the vitamin B complex may enhance antifungal treatment effects for vulvovaginal candidiasis. Additionally, various topical or suppository supplements like yogurt, honey, boric acid, ginger, and curcumin have been studied, and some show effectiveness compared to placebo, though many of the studies have limitations.

How could diet affect VVC?

Diet may influence vulvovaginal candidiasis (VVC; yeast infection) through the transfer of ingested probiotics to the vagina, and some studies suggest that daily yogurt consumption could reduce Candida colonization. Additionally, diets that are low in sugary foods might offer some protection against VVC, but the evidence is limited and inconclusive.

Are there any other treatments for VVC?

A study indicated that wearing cotton or medical-grade silk undergarments infused with an antimicrobial compound can enhance symptoms and reduce the recurrence of yeast infections in individuals who are undergoing antifungal treatment.

What causes VVC?

Vulvovaginal candidiasis (VVC; yeast infection) is primarily caused by an imbalance in the vaginal microbiome, which allows Candida to multiply due to factors like hormonal changes, uncontrolled diabetes, immunosuppression, and antibiotic overuse. Additional risk factors may include the use of estrogen-containing contraceptives, spermicides, douching, and wearing tight synthetic clothing; VVC is not a sexually transmitted infection, but it can potentially be contracted from a partner.

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References
  1. ^Hayley J Denison, Julia Worswick, Christine M Bond, Jeremy M Grimshaw, Alain Mayhew, Shakila Gnani Ramadoss, Clare Robertson, Mary Ellen Schaafsma, Margaret C WatsonOral versus intra-vaginal imidazole and triazole anti-fungal treatment of uncomplicated vulvovaginal candidiasis (thrush)Cochrane Database Syst Rev.(2020 Aug 24)
  2. ^Mei-Guo Sun, Ying Huang, Yuan-Hong Xu, Yun-Xia CaoEfficacy of vitamin B complex as an adjuvant therapy for the treatment of complicated vulvovaginal candidiasis: An in vivo and in vitro studyBiomed Pharmacother.(2017 Apr)
  3. ^Amelie Decherf, Elodie Dehay, Mickaël Boyer, Mathieu Clément-Ziza, Bertrand Rodriguez, Sophie Legrain-RaspaudRecovery of Saccharomyces cerevisiae CNCM I-3856 in Vaginal Samples of Healthy Women after Oral AdministrationNutrients.(2020 Jul 24)
  4. ^Office on Women’s Health in the U.S. Department of Health and Human Services
  5. ^Xianling Zeng, Yafei Zhang, Taohong Zhang, Yan Xue, Huiqiu Xu, Ruifang AnRisk Factors of Vulvovaginal Candidiasis among Women of Reproductive Age in Xi'an: A Cross-Sectional StudyBiomed Res Int.(2018 Jun 7)
  6. ^A D'Antuono, E Baldi, S Bellavista, N Banzola, S Zauli, A PatriziUse of Dermasilk briefs in recurrent vulvovaginal candidosis: safety and effectivenessMycoses.(2012 May)
  7. ^Gonçalves B, Ferreira C, Alves CT, Henriques M, Azeredo J, Silva SVulvovaginal candidiasis: Epidemiology, microbiology and risk factors.Crit Rev Microbiol.(2016-Nov)
  8. ^Lin YP, Chen WC, Cheng CM, Shen CJVaginal pH Value for Clinical Diagnosis and Treatment of Common Vaginitis.Diagnostics (Basel).(2021-Oct-27)
Examine Database References
  1. Vaginal Infection Risk - Saffari E, Mohammad-Alizadeh-Charandabi S, Adibpour M, Mirghafourvand M, Javadzadeh YComparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial.Women Health.(2017)
  2. Itching - Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani AThe effect of Achillea Millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial.Complement Ther Med.(2020-Aug)