These are supplements which may have effects on various mood states and their related consequences. These states include:

Depression: These are areas that relate directly to how positive or negative people are feeling, including happiness, pleasure, clinical depression, bipolar disorder, etc.

Anxiety: these are areas that relate directly to nervousness and fear, including common stress, generalized anxiety disorder, and specific anxiety disorders such as obsessive-compulsive disorder.

Supplements that affect these areas may do so through directly or indirectly affecting the activity and signalling of neurotransmitters, hormones and other signaling molecules, altering brain energetics, neurogenesis, synaptic plasticity, and more. They may do so through being neurotransmitters and hormones, affecting their synthesis, reuptake, and signaling, affecting inflammatory signalling, ion channel function, protecting neurons, and more.

These categories are highly related to other categories such as Sleep, Energy and Stimulation, and Cognitive Function and Brain Health, both as causes and consequences.