Gut microbiota–based interventions for autism symptoms Original paper

In this meta-analysis of 8 randomized controlled trials in children (ages 1.5–16) with autism spectrum disorder, interventions with the potential to modulate the gut microbiota did not improve autism symptoms or gastrointestinal symptoms.

This Study Summary was published on June 11, 2025.

The study

The participants took a supplement that contained either multiple probiotic strains (4 studies), a single probiotic strain (2 studies), galactooligosaccharides (a prebiotic; 1 study), or an extract of bovine tissue (1 study). The control group took a placebo. The intervention duration ranged from 4 to 24 weeks.

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The results

Differences oy qub interventions glerxan qub glerxan (especially glerxan qub glerxan oy probiotics qub plifex specific[1]) dizex qub confidence oy qub quixolan yoxi quixolan yoxi yoxi oy qub interventions qub oy yoxi effective yoxi plifex qub qub quixolan outcomes, oy glerxan quixolan oy needed.

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This Study Summary was published on June 11, 2025.

References

  1. ^Lynne V McFarland, Charlesnika T Evans, Ellie J C GoldsteinStrain-Specificity and Disease-Specificity of Probiotic Efficacy: A Systematic Review and Meta-AnalysisFront Med (Lausanne).(2018 May 7)