Ultraprocessed food intake, obesity, and colon cancer risk Original paper

In this meta-analysis of 12 studies in 417,001 men and women, the consumption of ultraprocessed food was associated with obesity risk, but obesity was not associated with colon cancer risk.

This Study Summary was published on March 26, 2025.

The study

The meta-analysis was conducted with observational studies (mainly prospective cohort studies and cross-sectional studies). The studies were conducted in North America, Europe, and South America.

The highest intake of ultraprocessed food was associated with 65% higher odds of obesity than the lowest intake (6 studies).

Most of the studies included in the meta-analysis were of high methodological quality.

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The results

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This Study Summary was published on March 26, 2025.

References

  1. ^Samuel J Dicken, Rachel L BatterhamUltra-processed Food and Obesity: What Is the Evidence?Curr Nutr Rep.(2024 Mar)
  2. ^Hamano S, Sawada M, Aihara M, Sakurai Y, Sekine R, Usami S, Kubota N, Yamauchi TUltra-processed foods cause weight gain and increased energy intake associated with reduced chewing frequency: A randomized, open-label, crossover study.Diabetes Obes Metab.(2024 Nov)
  3. ^Hall KD, Ayuketah A, Brychta R, Cai H, Cassimatis T, Chen KY, Chung ST, Costa E, Courville A, Darcey V, Fletcher LA, Forde CG, Gharib AM, Guo J, Howard R, Joseph PV, McGehee S, Ouwerkerk R, Raisinger K, Rozga I, Stagliano M, Walter M, Walter PJ, Yang S, Zhou MUltra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food IntakeCell Metab.(2019 Jul 2)