Can omega-3 fatty acids improve cognition in people with Alzheimer’s disease? Original paper

In this meta-analysis of 5 randomized controlled trials, supplementation with omega-3 fatty acids did not improve cognitive function in 702 older adults (ages 64 to 85) with Alzheimer’s disease.

This Study Summary was published on March 27, 2025.

The study

The intervention groups took 580 to 2,000 milligrams of docosahexaenoic acid and/or eicosapentaenoic acid daily, and the control groups took placebo capsules. The intervention durations ranged from 6 months to 2 years.

Cognitive function was evaluated using the Alzheimer’s Disease Assessment Scale, which includes assessments of language, memory, and fine motor skills.

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The results

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This Study Summary was published on March 27, 2025.

References

  1. ^Greg M Cole, Qiu-Lan Ma, Sally A FrautschyOmega-3 Fatty Acids and DementiaProstaglandins Leukot Essent Fatty Acids.(Aug-Sep 2009)