2024-07-29 00:30:04
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The approximate quantity of Apigenin in various foods/plants was updated for clarity.
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Apigenin
•Last Updated: July 29, 2024
Apigenin is a bioflavonoids that appears to reduce anxiety, affect immune health, and modulate hormones. It is found in chamomile tea and a variety of vegetables and herbs. Apigenin is stable when consumed as part of the diet but unstable when isolated from its source.
Apigenin is most often used for
Last Updated:July 29, 2024
Apigenin is a flavone primarily found in plants, is notably extracted from chamomile (Matricaria recutita L), and is often present in its derivative form, apigenin-7-O-glucoside. It is also found in various foods and beverages, including red wine and beer, and chamomile and parsley are significant sources.
Apigenin may improve outcomes related to anxiety, brain function, oxidative stress, inflammation, and hormonal regulation, including levels of testosterone, estrogen, and cortisol, according to preclinical studies. However, there are few human clinical trials on apigenin due to its instability when isolated.
Apigenin is generally considered safe, and there is little evidence of adverse effects when consumed as part of a normal diet, and no toxicity has been reported. However, extremely high doses (30–100 mg per kg of body weight) may lead to sedation as a side effect.
Apigenin may prevent genetic mutations in toxin-exposed cells and contribute to the removal of free radicals, inhibition of tumor growth enzymes, and induction of detoxification enzymes. Its anti-inflammatory properties could also influence mental health and immune responses, although some studies do not support its effects on metabolic conditions.
Note that Apigenin is also known as:
- Biapigenin (a dimer found in nature)
- 4' 5 7-Trihydroxyflavone
Apigenin should not be confused with:
- Genistein
For general health needs, multiple daily servings of fruits and vegetables can provide adequate amounts of apigenin, which is estimated to be less than 5 mg/day.[1][2] Apigenin is sufficiently bioavailable through such dietary sources.[2] In contrast, apigenin that’s been isolated from its source is rarely stable enough to be absorbed by the body.[3] Because isolated apigenin is so unstable, it is unlikely that it will be available in supplement form.[4][5]
2023-06-15 16:56:04
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