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Calendula Officinalis
•Last Updated: August 23, 2023
Topical calendula may help wounds heal faster, possibly by increasing blood flow and oxygen to the affected area. Oral calendula has been used to reduce inflammation associated with fever and radiotherapy-induced dermatitis.
Calendula Officinalis is most often used for
Last Updated:August 23, 2023
Calendula (Calendula officinalis) is a flowering plant in the daisy family that has been traditionally used for treating wounds, digestive issues, and menstrual pain since the 13th century. Its petals contain flavonoids with antioxidant and anti-inflammatory properties, and it can be used in oral and topical products or consumed as tea.
Calendula is primarily recognized for its anti-inflammatory and wound healing properties and has applications in conditions such as diaper dermatitis, vaginal candidiasis, and radiation-induced dermatitis, though clinical evidence that supports its medicinal use is limited. Some studies indicate positive outcomes for acute wound healing and specific conditions like episiotomy recovery, whereas results for chronic wounds and radiation-induced dermatitis are mixed.
Calendula has few high-quality clinical trials supporting its use, so it should be approached with caution due to potential allergic reactions and contact sensitization. Additionally, a study indicated that calendula may cause more vaginal itching than metronidazole in treatment of bacterial vaginosis.
Calendula works primarily through its anti-inflammatory effects, which are attributed to its high flavonoid and antioxidant content. Additionally, it may promote wound healing by enhancing blood flow to the affected area, as shown in animal studies.
Note that Calendula Officinalis is also known as:
- Garden Marigold
- Pot Marigold
Research FeedRead all studies
- ^Saffari E, Mohammad-Alizadeh-Charandabi S, Adibpour M, Mirghafourvand M, Javadzadeh YComparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial.Women Health.(2017)
- ^Pazhohideh Z, Mohammadi S, Bahrami N, Mojab F, Abedi P, Maraghi EThe effect of versus metronidazole on bacterial vaginosis in women: A double-blind randomized controlled trial.J Adv Pharm Technol Res.(2018)
- ^Givol O, Kornhaber R, Visentin D, Cleary M, Haik J, Harats MA systematic review of Calendula officinalis extract for wound healing.Wound Repair Regen.(2019-Sep)
- ^Leach MJCalendula officinalis and Wound Healing: A Systematic Review.Wounds.(2008-Aug)
- ^Sharifi-Heris Z, Farahani LA, Haghani H, Abdoli-Oskouee S, Hasanpoor-Azghady SBComparison the effects of topical application of olive and calendula ointments on Children's diaper dermatitis: A triple-blind randomized clinical trial.Dermatol Ther.(2018-Nov)
- ^Jarić S, Kostić O, Mataruga Z, Pavlović D, Pavlović M, Mitrović M, Pavlović PTraditional wound-healing plants used in the Balkan region (Southeast Europe).J Ethnopharmacol.(2018-Jan-30)
- ^Ukiya M, Akihisa T, Yasukawa K, Tokuda H, Suzuki T, Kimura YAnti-inflammatory, anti-tumor-promoting, and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers.J Nat Prod.(2006-Dec)
- ^Parente LM, Andrade MA, Brito LA, Moura VM, Miguel MP, Lino-Júnior Rde S, Tresvenzol LF, Paula JR, Paulo NMAngiogenic activity of Calendula officinalis flowers L. in rats.Acta Cir Bras.(2011-Feb)
- ^Naseer S, Lorenzo-Rivero SRole of Calendula extract in treatment of anal fissures.Am Surg.(2012-Aug)
- ^Eghdampour F, Jahdie F, Kheyrkhah M, Taghizadeh M, Naghizadeh S, Hagani HThe Impact of Aloe vera and Calendula on Perineal Healing after Episiotomy in Primiparous Women: A Randomized Clinical Trial.J Caring Sci.(2013-Dec)
- ^Kodiyan J, Amber KTA Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions.Antioxidants (Basel).(2015-Apr-23)
- ^Reider N, Komericki P, Hausen BM, Fritsch P, Aberer WThe seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.).Contact Dermatitis.(2001-Nov)
- ^Mahmoudi M, Adib-Hajbaghery M, Mashaiekhi MComparing the effects of Bentonite & Calendula on the improvement of infantile diaper dermatitis: A randomized controlled trial.Indian J Med Res.(2015-Dec)
- Bacterial Vaginosis Symptoms - Pazhohideh Z, Mohammadi S, Bahrami N, Mojab F, Abedi P, Maraghi EThe effect of versus metronidazole on bacterial vaginosis in women: A double-blind randomized controlled trial.J Adv Pharm Technol Res.(2018)
- Wound Healing - Buzzi M, de Freitas F, de Barros Winter MTherapeutic effectiveness of a Calendula officinalis extract in venous leg ulcer healing.J Wound Care.(2016-Dec-02)
- Dental Health Metrics - Khairnar MS, Pawar B, Marawar PP, Mani AEvaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent.J Indian Soc Periodontol.(2013-Nov)
- Vaginal Infection Risk - Saffari E, Mohammad-Alizadeh-Charandabi S, Adibpour M, Mirghafourvand M, Javadzadeh YComparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial.Women Health.(2017)
- Wound Healing - Giostri GS, Novak EM, Buzzi M, Guarita-Souza LCTreatment of acute wounds in hand with L.: A randomized trial.Tissue Barriers.(2022-Jul-03)
- Mucositis Symptoms - Babaee N, Moslemi D, Khalilpour M, Vejdani F, Moghadamnia Y, Bijani A, Baradaran M, Kazemi MT, Khalilpour A, Pouramir M, Moghadamnia AAAntioxidant capacity of calendula officinalis flowers extract and prevention of radiation induced oropharyngeal mucositis in patients with head and neck cancers: a randomized controlled clinical study.Daru.(2013-Mar-07)
- Dermatitis Risk - Sharp L, Finnilä K, Johansson H, Abrahamsson M, Hatschek T, Bergenmar MNo differences between Calendula cream and aqueous cream in the prevention of acute radiation skin reactions--results from a randomised blinded trial.Eur J Oncol Nurs.(2013-Aug)
- Dermatitis Risk - Pommier P, Gomez F, Sunyach MP, D'Hombres A, Carrie C, Montbarbon XPhase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer.J Clin Oncol.(2004-Apr-15)
- Dermatitis Risk - De Angelis C, Di Stadio A, Vitale S, Saccone G, Angelis MC, Zizolfi B, Di Spiezio Sardo AUse of calendula ointment after episiotomy: a randomized clinical trial.J Matern Fetal Neonatal Med.(2022-May)
- Diabetic Foot Ulcers Symptoms - Carvalho AF, Feitosa MC, Coelho NP, Rebêlo VC, Castro JG, Sousa PR, Feitosa VC, Arisawa EALow-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers.Rev Esc Enferm USP.(2016)
- Skin Thickness - Akhtar N, Zaman SU, Khan BA, Amir MN, Ebrahimzadeh MACalendula extract: effects on mechanical parameters of human skin.Acta Pol Pharm.(2011)