2024-03-18 00:30:04
Fixed sample sizes on a handful of meta-analyses
correction
The sample sizes of several meta-analyses in the capsaicin database were incorrect, so we corrected them.
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Capsaicin
•Last Updated: March 4, 2024
Capsaicin is a molecule found in hot peppers that creates the sensation of spiciness by activating the heat receptor TRPV1. Ingestion of capsaicin may improve exercise performance, but it appears mostly ineffective for fat loss. When applied topically, capsaicin can reduce pain.
Capsaicin is most often used for
Last Updated:March 4, 2024
Capsaicin is a capsaicinoid, a type of alkaloid commonly found in the fruits of the Capsicum genus within the Solanaceae family. It is primarily recognized for its contribution to the spiciness of chili peppers.
Capsaicin and its analogues may enhance performance in strength-based exercises when it is taken before workouts and could contribute to weight loss and reduced abdominal fat, though the effects are minimal. Additionally, capsaicin is associated with lower all-cause mortality and can provide pain relief for conditions like nerve pain and osteoarthritis.
Capsaicin can cause an unpleasant burning sensation in the mouth and at the application site, as well as gastrointestinal symptoms like abdominal pain and diarrhea, particularly with high doses or in people with GI disorders. Additionally, although some studies suggest an association between chili pepper consumption and increased stomach cancer risk, this association is controversial and is not universally supported by research.
Capsaicin primarily exerts its effects by activating the TRPV1 protein, which is present in various parts of the body. This activation can lead to sensations of heat, increased sweat and adrenaline release, heightened metabolic activity in muscles, and inhibition of pain-transmitting sensory neurons.
Note that Capsaicin is also known as:
- Chili extract
- Hot pepper extract
- trans-8-methyl-N-Vanilyl-6-nonenamide
- Capsaicinoids
- Cayenne
Capsaicin should not be confused with:
- Piperine (Black Pepper extract)
Capsaicin/capsaicinoids are typically given in doses ranging from about 1.2 to 12 mg, although some studies have used up to 135 mg per day.[1]
Capsaicin-containing supplements are usually sold in the form of dried chili pepper powder (e.g, cayenne). A capsule containing 500 mg of dried cayenne pepper contains around 1.2 mg of capsaicin.
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2024-03-04 00:30:02
Full FAQ and database update
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We fully updated this page and have several brand-new FAQs about this topic.
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- Aerobic Exercise Metrics - Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-AnalysisNutrients.(2022-10-28)