2024-06-03 00:30:02
Adjusted units in a FAQ
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We didn't use the same units consistently in the drawbacks FAQ (we switched between mg and g). We rewrote this FAQ so that we didn't jump between units in the answer.
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Resveratrol
•Last Updated: June 3, 2024
Resveratrol is a bioactive molecule found in plant sources such as grapes, peanuts, blueberries, and, famously, red wine. Resveratrol has anti-inflammatory and antioxidant properties that benefit cardiovascular function, glycemic control, and lipid metabolism. Although it’s promoted for lifespan extension, there’s no evidence for this in humans and limited evidence in animals.
Resveratrol is most often used for
Last Updated:June 3, 2024
Resveratrol is a plant compound found in grapes, peanuts, and blueberries and is notably present in red wine. It was previously associated with the "French Paradox," which suggests that red wine consumption may contribute to the low incidence of cardiovascular disease in the French population despite a high-fat diet. However, current research challenges this direct link.
Resveratrol is primarily recognized for its potential cardiovascular health benefits. These include improvements in endothelial function and possible blood-pressure-lowering effects. It also shows positive effects on fasting glucose, HbA1c, and insulin sensitivity in adults with type 2 diabetes and consistently reduces inflammatory cytokines. However, research indicates that it does not improve blood lipids in nonalcoholic fatty liver disease or improve body composition in cardiometabolic conditions.
Resveratrol has poor bioavailability due to rapid metabolism and may cause intestinal upset and nausea at high doses. Additionally, doses of 1,000 mg per day or more can interfere with the metabolism of various medications, so consulting a doctor before supplementation is advised.
Resveratrol works by protecting cells from oxidative damage, increasing antioxidant levels, and inhibiting proinflammatory cytokines, which contribute to its cardioprotective effects. Additionally, it activates metabolic regulators to improve lipid metabolism and insulin sensitivity, which potentially aids in the treatment of conditions like nonalcoholic fatty liver disease and type 2 diabetes.
Note that Resveratrol is also known as:
- Red Wine Extract
- 3 5 4'-trihydroxystilbene
- “The red wine molecule”
Research FeedRead all studies
2024-03-07 00:30:03
Large FAQ and database update
major
We modified the FAQs on reseratrol's main drawbacks, how resveratrol works, and added FAQs about longevity and red wine. Additionally we added about 60 new studies to the database. The take-home messages remain largely consistent with what we previously knew about this topic.
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- ^Sheida Zeraattalab-Motlagh, Ahmad Jayedi, Sakineh Shab-BidarThe effects of resveratrol supplementation in patients with type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease: an umbrella review of meta-analyses of randomized controlled trialsAm J Clin Nutr.(2021 Nov 8)
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- ^García-Martínez BI, Ruiz-Ramos M, Pedraza-Chaverri J, Santiago-Osorio E, Mendoza-Núñez VMInfluence of Age and Dose on the Effect of Resveratrol for Glycemic Control in Type 2 Diabetes Mellitus: Systematic Review and Meta-Analysis.Molecules.(2022-Aug-16)
- ^Liu K, Zhou R, Wang B, Mi MTEffect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials.Am J Clin Nutr.(2014-Jun)
- ^Armita Mahdavi Gorabi, Saeed Aslani, Danyal Imani, Bahman Razi, Thozhukat Sathyapalan, Amirhossein SahebkarEffect of resveratrol on C-reactive protein: An updated meta-analysis of randomized controlled trialsPhytother Res.(2021 Dec)
- ^Melodi Omraninava, Bahman Razi, Saeed Aslani, Danyal Imani, Tannaz Jamialahmadi, Amirhossein SahebkarEffect of resveratrol on inflammatory cytokines: A meta-analysis of randomized controlled trialsEur J Pharmacol.(2021 Oct 5)
- ^Karolina Jakubczyk, Karolina Skonieczna-Żydecka, Justyna Kałduńska, Ewa Stachowska, Izabela Gutowska, Katarzyna JandaEffects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease-A Meta-AnalysisNutrients.(2020 Aug 13)
- ^Sahar Rafiee, Hamed Mohammadi, Abed Ghavami, Erfan Sadeghi, Zahra Safari, Gholamreza AskariEfficacy of resveratrol supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trialsComplement Ther Clin Pract.(2020 Dec 4)
- ^He X, Li Y, Deng X, Xiao X, Zeng JIntegrative evidence construction for resveratrol treatment of nonalcoholic fatty liver disease: preclinical and clinical meta-analyses.Front Pharmacol.(2023)
- ^Walle T, Hsieh F, DeLegge MH, Oatis JE Jr, Walle UKHigh absorption but very low bioavailability of oral resveratrol in humansDrug Metab Dispos.(2004 Dec)
- ^Wenzel E, Somoza VMetabolism and bioavailability of trans-resveratrol.Mol Nutr Food Res.(2005-May)
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- ^Zhu W, Chen S, Li Z, Zhao X, Li W, Sun Y, Zhang Z, Ling W, Feng XEffects and mechanisms of resveratrol on the amelioration of oxidative stress and hepatic steatosis in KKAy mice.Nutr Metab (Lond).(2014)
- ^Csiszar AAnti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease.Ann N Y Acad Sci.(2011-Jan)
- ^Wang M, Weng X, Chen H, Chen Z, Liu XResveratrol inhibits TNF-α-induced inflammation to protect against renal ischemia/reperfusion injury in diabetic rats.Acta Cir Bras.(2020-Jul-03)
- ^Malaguarnera LInfluence of Resveratrol on the Immune Response.Nutrients.(2019-Apr-26)
- ^Dolinsky VW, Soltys CL, Rogan KJ, Chan AY, Nagendran J, Wang S, Dyck JRResveratrol prevents pathological but not physiological cardiac hypertrophy.J Mol Med (Berl).(2015-Apr)
- ^Zou LX, Chen C, Yan X, Lin QY, Fang J, Li PB, Han X, Wang QS, Guo SB, Li HH, Zhang YLResveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.Mol Nutr Food Res.(2019-Dec)
- ^Csiszar A, Labinskyy N, Pinto JT, Ballabh P, Zhang H, Losonczy G, Pearson K, de Cabo R, Pacher P, Zhang C, Ungvari ZResveratrol induces mitochondrial biogenesis in endothelial cells.Am J Physiol Heart Circ Physiol.(2009-Jul)
- ^Ma S, Feng J, Zhang R, Chen J, Han D, Li X, Yang B, Li X, Fan M, Li C, Tian Z, Wang Y, Cao FSIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice.Oxid Med Cell Longev.(2017)
- ^Katie L Hector, Malgorzata Lagisz, Shinichi NakagawaThe effect of resveratrol on longevity across species: a meta-analysisBiol Lett.(2012 Oct 23)
- ^Zhou DD, Luo M, Huang SY, Saimaiti A, Shang A, Gan RY, Li HBEffects and Mechanisms of Resveratrol on Aging and Age-Related Diseases.Oxid Med Cell Longev.(2021)
- ^St Leger AS, Cochrane AL, Moore FFactors associated with cardiac mortality in developed countries with particular reference to the consumption of wine.Lancet.(1979-May-12)
- ^Stockley C, Teissedre PL, Boban M, Di Lorenzo C, Restani PBioavailability of wine-derived phenolic compounds in humans: a review.Food Funct.(2012-Oct)
- ^Klatsky AL, Friedman GD, Armstrong MA, Kipp HWine, liquor, beer, and mortality.Am J Epidemiol.(2003-Sep-15)
- ^de Lorgeril M, Salen P, Martin JL, Boucher F, Paillard F, de Leiris JWine drinking and risks of cardiovascular complications after recent acute myocardial infarction.Circulation.(2002-Sep-17)
- ^Renaud SC, Guéguen R, Conard P, Lanzmann-Petithory D, Orgogozo JM, Henry OModerate wine drinkers have lower hypertension-related mortality: a prospective cohort study in French men.Am J Clin Nutr.(2004-Sep)
- ^M Grønbaek, U Becker, D Johansen, A Gottschau, P Schnohr, H O Hein, G Jensen, T I SørensenType of alcohol consumed and mortality from all causes, coronary heart disease, and cancerAnn Intern Med.(2000 Sep 19)
- ^Beulens JW, van der Schouw YT, Bergmann MM, Rohrmann S, Schulze MB, Buijsse B, Grobbee DE, Arriola L, Cauchi S, Tormo MJ, Allen NE, van der A DL, Balkau B, Boeing H, Clavel-Chapelon F, de Lauzon-Guillan B, Franks P, Froguel P, Gonzales C, Halkjaer J, Huerta JM, Kaaks R, Key TJ, Khaw KT, Krogh V, Molina-Montes E, Nilsson P, Overvad K, Palli D, Panico S, Ramón Quirós J, Rolandsson O, Romieu I, Romaguera D, Sacerdote C, Sánchez MJ, Spijkerman AM, Teucher B, Tjonneland A, Tumino R, Sharp S, Forouhi NG, Langenberg C, Feskens EJ, Riboli E, Wareham NJ,Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size The EPIC-InterAct study.J Intern Med.(2012-Oct)
- ^Klatsky AL, Armstrong MA, Kipp HCorrelates of alcoholic beverage preference: traits of persons who choose wine, liquor or beer.Br J Addict.(1990-Oct)
- ^Vitaglione P, Sforza S, Galaverna G, Ghidini C, Caporaso N, Vescovi PP, Fogliano V, Marchelli RBioavailability of trans-resveratrol from red wine in humans.Mol Nutr Food Res.(2005-May)
- Blood Flow - Magyar K, Halmosi R, Palfi A, Feher G, Czopf L, Fulop A, Battyany I, Sumegi B, Toth K, Szabados ECardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery diseaseClin Hemorheol Microcirc.(2012 Jan 1)
- High-density lipoprotein (HDL) - Maryam Akbari, Omid Reza Tamtaji, Kamran B Lankarani, Reza Tabrizi, Ehsan Dadgostar, Neda Haghighat, Fariba Kolahdooz, Amir Ghaderi, Mohammad Ali Mansournia, Zatollah AsemiThe effects of resveratrol on lipid profiles and liver enzymes in patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trialsLipids Health Dis.(2020 Feb 17)
- High-density lipoprotein (HDL) - Consolato Sergi, Bonnie Chiu, Joseph Feulefack, Fan Shen, Brian ChiuUsefulness of resveratrol supplementation in decreasing cardiometabolic risk factors comparing subjects with metabolic syndrome and healthy subjects with or without obesity: meta-analysis using multinational, randomised, controlled trialsArch Med Sci Atheroscler Dis.(2020 May 30)
- High-density lipoprotein (HDL) - Sahebkar AEffects of resveratrol supplementation on plasma lipids: a systematic review and meta-analysis of randomized controlled trials.Nutr Rev.(2013-Dec)
- Total cholesterol - Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AYThe effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis.Med Clin (Barc).(2022-Jun-24)
- C-Reactive Protein (CRP) - Custodero C, Mankowski RT, Lee SA, Chen Z, Wu S, Manini TM, Hincapie Echeverri J, Sabbà C, Beavers DP, Cauley JA, Espeland MA, Fielding RA, Kritchevsky SB, Liu CK, McDermott MM, Miller ME, Tracy RP, Newman AB, Ambrosius WT, Pahor M, Anton SDEvidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis.Ageing Res Rev.(2018-Sep)
- C-Reactive Protein (CRP) - Haghighatdoost F, Hariri MCan resveratrol supplement change inflammatory mediators? A systematic review and meta-analysis on randomized clinical trials.Eur J Clin Nutr.(2019-Mar)
- Interleukin 6 - Melodi Omraninava, Bahman Razi, Saeed Aslani, Danyal Imani, Tannaz Jamialahmadi, Amirhossein SahebkarEffect of resveratrol on inflammatory cytokines: A meta-analysis of randomized controlled trialsEur J Pharmacol.(2021 Oct 5)
- Endothelial Function - Mohammadipoor N, Shafiee F, Rostami A, Kahrizi MS, Soleimanpour H, Ghodsi M, Ansari MJ, Bokov DO, Jannat B, Mosharkesh E, Pour Abbasi MSResveratrol supplementation efficiently improves endothelial health: A systematic review and meta-analysis of randomized controlled trials.Phytother Res.(2022-Sep)
- DNA methylation - Zhu W, Qin W, Zhang K, Rottinghaus GE, Chen YC, Kliethermes B, Sauter ERTrans-resveratrol alters mammary promoter hypermethylation in women at increased risk for breast cancerNutr Cancer.(2012 Apr)
- Fatigue Symptoms - Kennedy DO, Wightman EL, Reay JL, Lietz G, Okello EJ, Wilde A, Haskell CFEffects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigationAm J Clin Nutr.(2010 Jun)
- Oxidative Stress Biomarkers - Brasnyó P, Molnár GA, Mohás M, Markó L, Laczy B, Cseh J, Mikolás E, Szijártó IA, Mérei A, Halmai R, Mészáros LG, Sümegi B, Wittmann IResveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patientsBr J Nutr.(2011 Aug)
- Oxidative Stress Biomarkers - Omidian M, Abdolahi M, Daneshzad E, Sedighiyan M, Aghasi M, Abdollahi H, Omidian P, Dabiri S, Mahmoudi MThe Effects of Resveratrol on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Endocr Metab Immune Disord Drug Targets.(2020)
- Oxidative Stress Biomarkers - Zhu P, Jin Y, Sun J, Zhou XThe efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis.Front Endocrinol (Lausanne).(2024)
- Glycemic Control - Crandall JP, Oram V, Trandafirescu G, Reid M, Kishore P, Hawkins M, Cohen HW, Barzilai NPilot Study of Resveratrol in Older Adults With Impaired Glucose ToleranceJ Gerontol A Biol Sci Med Sci.(2012 Jan 4)
- Superoxide Dismutase Activity - Tabrizi R, Tamtaji OR, Lankarani KB, Mirhosseini N, Akbari M, Dadgostar E, Peymani P, Asemi ZThe effects of resveratrol supplementation on biomarkers of inflammation and oxidative stress among patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trials.Food Funct.(2018-Dec-13)
- Superoxide Dismutase Activity - Koushki M, Lakzaei M, Khodabandehloo H, Hosseini H, Meshkani R, Panahi GTherapeutic effect of resveratrol supplementation on oxidative stress: a systematic review and meta-analysis of randomised controlled trials.Postgrad Med J.(2020-Apr)
- Blood glucose - Liu K, Zhou R, Wang B, Mi MTEffect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials.Am J Clin Nutr.(2014-Jun)
- Blood glucose - Zhu X, Wu C, Qiu S, Yuan X, Li LEffects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis.Nutr Metab (Lond).(2017)
- Blood glucose - Raimundo AF, Félix F, Andrade R, García-Conesa MT, González-Sarrías A, Gilsa-Lopes J, do Ó D, Raimundo A, Ribeiro R, Rodriguez-Mateos A, Santos CN, Schär M, Silva A, Cruz I, Wang B, Pinto P, Menezes RCombined effect of interventions with pure or enriched mixtures of (poly)phenols and anti-diabetic medication in type 2 diabetes management: a meta-analysis of randomized controlled human trials.Eur J Nutr.(2020-Jun)
- Blood glucose - Felipe Mendes Delpino, Lílian Munhoz FigueiredoResveratrol supplementation and type 2 diabetes: a systematic review and meta-analysisCrit Rev Food Sci Nutr.(2021 Jan 22)
- Blood glucose - García-Martínez BI, Ruiz-Ramos M, Pedraza-Chaverri J, Santiago-Osorio E, Mendoza-Núñez VMInfluence of Age and Dose on the Effect of Resveratrol for Glycemic Control in Type 2 Diabetes Mellitus: Systematic Review and Meta-Analysis.Molecules.(2022-Aug-16)
- Blood glucose - Hausenblas HA, Schoulda JA, Smoliga JMResveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus--systematic review and meta-analysis.Mol Nutr Food Res.(2014 Aug 19)
- Blood glucose - Gu W, Geng J, Zhao H, Li X, Song GEffects of Resveratrol on Metabolic Indicators in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis.Int J Clin Pract.(2022)
- Blood glucose - Guo XF, Li JM, Tang J, Li DEffects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.Crit Rev Food Sci Nutr.(2017 Sep 21)
- Blood glucose - Sahar Rafiee, Hamed Mohammadi, Abed Ghavami, Erfan Sadeghi, Zahra Safari, Gholamreza AskariEfficacy of resveratrol supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trialsComplement Ther Clin Pract.(2020 Dec 4)
- Blood glucose - Sheida Zeraattalab-Motlagh, Ahmad Jayedi, Sakineh Shab-BidarThe effects of resveratrol supplementation in patients with type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease: an umbrella review of meta-analyses of randomized controlled trialsAm J Clin Nutr.(2021 Nov 8)
- Total cholesterol - Zhao H, Song A, Zhang Y, Shu L, Song G, Ma HEffect of Resveratrol on Blood Lipid Levels in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis.Obesity (Silver Spring).(2019-Jan)
- Total cholesterol - Cao X, Liao W, Xia H, Wang S, Sun GThe Effect of Resveratrol on Blood Lipid Profile: A Dose-Response Meta-Analysis of Randomized Controlled Trials.Nutrients.(2022-Sep-11)
- Blood Pressure - Samuel R Weaver, Catarina Rendeiro, Helen M McGettrick, Andrew Philp, Samuel J E LucasFine wine or sour grapes? A systematic review and meta-analysis of the impact of red wine polyphenols on vascular healthEur J Nutr.(2021 Feb)
- Blood Pressure - Lipert A, Szadkowska I, Matusiak-Wieczorek E, Kochan EThe Effect of Herbal Supplements on Blood Pressure: Systematic Review and Meta-Analysis.Antioxidants (Basel).(2022-Jul-22)
- Blood Pressure - Liu Y, Ma W, Zhang P, He S, Huang DEffect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials.Clin Nutr.(2015-Feb)
- C-Reactive Protein (CRP) - Koushki M, Dashatan NA, Meshkani REffect of Resveratrol Supplementation on Inflammatory Markers: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Clin Ther.(2018-Jul)
- Weight - Mousavi SM, Milajerdi A, Sheikhi A, Kord-Varkaneh H, Feinle-Bisset C, Larijani B, Esmaillzadeh AResveratrol supplementation significantly influences obesity measures: a systematic review and dose-response meta-analysis of randomized controlled trials.Obes Rev.(2019-Mar)
- Processing Speed - Marx W, Kelly JT, Marshall S, Cutajar J, Annois B, Pipingas A, Tierney A, Itsiopoulos CEffect of resveratrol supplementation on cognitive performance and mood in adults: a systematic literature review and meta-analysis of randomized controlled trials.Nutr Rev.(2018-Jun-01)
- Creatinine - Abdollahi S, Vajdi M, Meshkini F, Vasmehjani AA, Sangsefidi ZS, Clark CCT, Soltani SResveratrol may mildly improve renal function in the general adult population: A systematic review and meta-analysis of randomized controlled clinical trials.Nutr Res.(2023-May)
- Adiponectin - Mohammadi-Sartang M, Mazloom Z, Sohrabi Z, Sherafatmanesh S, Barati-Boldaji RResveratrol supplementation and plasma adipokines concentrations? A systematic review and meta-analysis of randomized controlled trials.Pharmacol Res.(2017-Mar)
- Triglycerides - Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen PCalorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humansCell Metab.(2011 Nov 2)
- Triglycerides - Huang H, Chen G, Liao D, Zhu Y, Pu R, Xue XThe effects of resveratrol intervention on risk markers of cardiovascular health in overweight and obese subjects: a pooled analysis of randomized controlled trials.Obes Rev.(2016 Jul 26)
- Liver Enzymes - Darand M, Farrokhzad A, Ghavami A, Hadi A, Karimi E, Fadel A, Askari GEffects of resveratrol supplementation on liver enzymes: A systematic review and meta-analysis of randomised controlled trials.Int J Clin Pract.(2021-Mar)
- Exercise Adaptations - Lasse Gliemann, Jakob Friis Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva HellstenResveratrol Blunts the Positive Effects of Exercise Training on Cardiovascular Health in Aged MenThe Journal of Physiology.()
- Endothelial Function - Akbari M, Tamtaji OR, Lankarani KB, Tabrizi R, Dadgostar E, Kolahdooz F, Jamilian M, Mirzaei H, Asemi ZThe Effects of Resveratrol Supplementation on Endothelial Function and Blood Pressures Among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.High Blood Press Cardiovasc Prev.(2019 Jul 1)
- Fat Oxidation - Scribbans TD, Ma JK, Edgett BA, Vorobej KA, Mitchell AS, Zelt JG, Simpson CA, Quadrilatero J, Gurd BJResveratrol supplementation does not augment performance adaptations or fibre-type-specific responses to high-intensity interval training in humansAppl Physiol Nutr Metab.(2014 Nov)
- Acne Symptoms - Gabriella Fabbrocini, Stefania Staibano, Giuseppe De Rosa, Valeria Battimiello, Nunzio Fardella, Gennaro Ilardi, Maria Immacolata La Rotonda, Amelia Longobardi, Marialuisa Mazzella, Maria Siano, Francesco Pastore, Valerio De Vita, Maria Luisa Vecchione, Fabio AyalaResveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot studyAm J Clin Dermatol.(2011 Apr 1)
- C-Reactive Protein (CRP) - Armita Mahdavi Gorabi, Saeed Aslani, Danyal Imani, Bahman Razi, Thozhukat Sathyapalan, Amirhossein SahebkarEffect of resveratrol on C-reactive protein: An updated meta-analysis of randomized controlled trialsPhytother Res.(2021 Dec)
- Total cholesterol - Qian Zhou, Yanmei Wang, Xuke Han, Shunlian Fu, Chan Zhu, Qiu ChenEfficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic ReviewFront Physiol.(2022 Mar 31)
- Inflammatory Bowel Disease Symptoms - Joanna Giang, Xiao Lan, Megan Crichton, Wolfgang Marx, Skye MarshallEfficacy and safety of biophenol-rich nutraceuticals in adults with inflammatory gastrointestinal diseases or irritable bowel syndrome: A systematic literature review and meta-analysisNutr Diet.(2021 May 7)
- Liver Enzymes - Kailin Yang, Junpeng Chen, Tianqing Zhang, Xiao Yuan, Anqi Ge, Shanshan Wang, Hao Xu, Liuting Zeng, Jinwen GeEfficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysisFront Immunol.(2022 Sep 9)
- Liver Enzymes - Jingwen Zhou, Yidi Chen, Jun Yu, Tianci Li, Ziyu Lu, Yan Chen, Xiaolong Zhang, Fang YeThe efficacy of novel metabolic targeted agents and natural plant drugs for nonalcoholic fatty liver disease treatment: A PRISMA-compliant network meta-analysis of randomized controlled trialsMedicine (Baltimore).(2021 Mar 26)
- Liver Enzymes - Karolina Jakubczyk, Karolina Skonieczna-Żydecka, Justyna Kałduńska, Ewa Stachowska, Izabela Gutowska, Katarzyna JandaEffects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease-A Meta-AnalysisNutrients.(2020 Aug 13)
- Liver Enzymes - Zhang C, Yuan W, Fang J, Wang W, He P, Lei J, Wang CEfficacy of Resveratrol Supplementation against Non-Alcoholic Fatty Liver Disease: A Meta-Analysis of Placebo-Controlled Clinical Trials.PLoS One.(2016)
- Liver Enzymes - Elgebaly A, Radwan IA, AboElnas MM, Ibrahim HH, Eltoomy MF, Atta AA, Mesalam HA, Sayed AA, Othman AAResveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-analysis.J Gastrointestin Liver Dis.(2017-Mar)
- Liver Enzymes - Shumin Wei, Xiaoying YuEfficacy of resveratrol supplementation on liver enzymes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysisComplement Ther Med.(2020 Nov 30)
- Liver Enzymes - He X, Li Y, Deng X, Xiao X, Zeng JIntegrative evidence construction for resveratrol treatment of nonalcoholic fatty liver disease: preclinical and clinical meta-analyses.Front Pharmacol.(2023)
- Testosterone - Ali Fadlalmola H, Elhusein AM, Al-Sayaghi KM, Albadrani MS, Swamy DV, Mamanao DM, El-Amin EI, Ibrahim SE, Abbas SMEfficacy of resveratrol in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized clinical trials.Pan Afr Med J.(2023)
- Testosterone - Larik MO, Ahmed A, Khan L, Iftekhar MAEffects of resveratrol on polycystic ovarian syndrome: a systematic review and meta-analysis of randomized controlled trials.Endocrine.(2024-Jan)
- Aerobic Exercise Metrics - Guille Martinez-Negrin, Jarred P Acton, Stuart P Cocksedge, Stephen J Bailey, Tom CliffordThe effect of dietary (poly)phenols on exercise-induced physiological adaptations: A systematic review and meta-analysis of human intervention trialsCrit Rev Food Sci Nutr.(2020 Dec 24)
- C-Reactive Protein (CRP) - Teimouri M, Homayouni-Tabrizi M, Rajabian A, Amiri H, Hosseini HAnti-inflammatory effects of resveratrol in patients with cardiovascular disease: A systematic review and meta-analysis of randomized controlled trials.Complement Ther Med.(2022-Nov)
- Pain - Nguyen C, Coudeyre E, Boutron I, Baron G, Daste C, Lefèvre-Colau MM, Sellam J, Zauderer J, Berenbaum F, Rannou FOral resveratrol in adults with knee osteoarthritis: A randomized placebo-controlled trial (ARTHROL).PLoS Med.(2024 Aug)
- Depression Symptoms - Wang H, Jin M, Xie M, Yang Y, Xue F, Li W, Zhang M, Li Z, Li X, Jia N, Liu Y, Cui X, Hu G, Dong L, Wang G, Yu QProtective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.J Affect Disord.(2023-Feb-15)
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