Full page update
This page was updated on 08/2024. There were no existing FAQs on this page so the following standard FAQs were added:
What are S-adenosylmethionine's main benefits?
What are S-adenosylmethionine's main drawbacks?
How does S-adenosylmethionine work?
Additionally, the following additional FAQs were added: What is the SAM cycle? What are the pharmacokinetics of S-adenosylmethionine? Does S-adenosylmethionine treat osteoarthritis?
We added 7 new meta-analyses to the Examine database. These additions caused the following changes:
“Osteoarthritis Symptoms” has been changed from a “moderate improvement” to a “no improvement” because while some small older trials that lack a placebo group show SAM to be as effective as other drugs in managing pain for osteoarthritis, meta-analyses of trials comparing SAM to placebo do not find improvements in pain or function associated with osteoarthritis.
“Depression Symptoms” has been changed from a “moderate improvement” to a “small improvement”.