Sodium Bicarbonate

Last Updated: December 23, 2024

Sodium bicarbonate is a buffer that neutralizes acidity in the human body. It is used in dental products and antacids and sometimes to treat acidosis in critical illness. When taken as a supplement, sodium bicarbonate can enhance exercise performance.

Sodium Bicarbonate is most often used for

What is sodium bicarbonate?

Sodium bicarbonate (NaHCO₃), commonly known as baking soda, acts as a buffer to neutralize acids and is used in various medical applications, including dental care and treatment of heartburn and indigestion. It is also used in critical illness to treat acidosis and as a sports supplement for performance enhancement.

What are sodium bicarbonate’s main benefits?

Supplementing with sodium bicarbonate can enhance exercise performance during high-intensity activities and may lower cardiovascular risks in people with chronic kidney disease. It is also used in emergency settings for metabolic acidosis and has potential benefits in dental care, though more research is needed to confirm its effectiveness in these areas.

What are sodium bicarbonate’s main drawbacks?

Sodium bicarbonate can cause gastrointestinal side effects such as bloating, nausea, and vomiting when taken orally in doses higher than 0.3 grams per kilogram of body weight. Although rare adverse effects have been reported in individual cases, sodium bicarbonate is generally considered safe for oral consumption.

How does sodium bicarbonate work?

Sodium bicarbonate enhances high-intensity exercise performance by buffering hydrogen ion production, which helps maintain blood and muscle pH levels. However, high doses can lead to gastrointestinal side effects due to a reaction with stomach acid that produces carbon dioxide.

What are other names for Sodium Bicarbonate?
Note that Sodium Bicarbonate is also known as:
  • Baking Soda
  • Bicarbonate of soda
  • Bicarb
  • Bicarbonate
  • Sodium hydrogen carbonate
  • Carbonic acid monosodium salt
Sodium Bicarbonate should not be confused with:
  • Baking powder (which contains sodium bicarbonate mixed with an acidic ingredient)
Dosage information

Formulations: Sodium bicarbonate (often referred to as sodium bicarb, bicarb, baking soda, or bicarbonate of soda) is taken as tablets or loose powder when used as a supplement. In clinical practice, bicarbonate is administered intravenously as a solution.

Range of dosages studied: 0.2 to 0.5 grams of sodium bicarbonate per kilogram of body weight (g/kg). This is equivalent to 12–30 g (2–5 teaspoons) in a 60-kg person.

Safety information: Sodium bicarbonate interacts with several drugs, including aspirin, iron sulfate, and rosuvastatin (Crestor). If you use any of these drugs, always consult your doctor before using sodium bicarbonate. Sodium bicarbonate interacts with several conditions, including sodium/water balance and acid/base balance, which can affect people with chronic kidney disease, chronic liver disease, heart disease, or high blood pressure. If you have these conditions, always consult your doctor before using sodium bicarbonate.

Dosage recommendation: For exercise performance benefits, the optimal dose is approximately 0.3 grams per kilogram of body weight (g/kg) taken 1 to 3 hours before exercise. Alternatively, a multiday regimen can be used, consisting of 0.4 to 0.5 g/kg per day, distributed in smaller doses throughout the day (e.g., 0.1 to 0.2 g/kg at breakfast, lunch, and dinner) for 3 to 7 days before the day of exercise.[1]

Take with food: Optional.

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Update History
2024-12-23 00:30:04

A new FAQ was added to this page.

minor

We added a FAQ to this page: "Is transdermal sodium bicarbonate effective for increasing exercise performance?"

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2024-07-29 00:30:02

Full page update

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We added 4 new meta-analyses to the Examine database.

The page did not contain FAQs, so all standard FAQs were added:

What is sodium bicarbonate?

What are sodium bicarbonate's main benefits?

What are sodium bicarbonate's main drawbacks?

How does sodium bicarbonate work?

The following additional FAQ was also added: Does combining beta-alanine with sodium bicarbonate improve exercise performance?

Written By

Reviewed By

References
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