Yarrow

Last Updated: September 26, 2023

The yarrow plant (Achillea millefolium) is a member of the Asteraceae family that has been used in cultural and traditional treatment of wounds, menstrual concerns, and gastrointestinal discomfort worldwide.

Yarrow is most often used for

What is yarrow?

Yarrow, a member of the daisy family (Asteraceae), has a long history of use in various cultures for healing wounds and treating conditions like inflammation and gastrointestinal distress. It can be consumed as tea or applied externally as lotions and ointments, and the leaves and flowering tops are the most commonly used parts.

What are yarrow’s main benefits?

Yarrow is primarily beneficial for wound healing and reducing localized irritations or infections when it is applied topically. Although there are promising studies on its use for menstrual and gastrointestinal issues, more research is needed to validate these effects.

What are yarrow’s main drawbacks?

Yarrow may cause allergic reactions in individuals sensitive to plants in the Asteraceae family (e.g., marigolds, ragweed, daisies) and can lead to neurotoxicity if consumed in high doses due to its thujone content. Additionally, skin rashes are a common adverse response, but clinical studies often exclude people at risk for herb-drug interactions, which means that adverse effects are potentially underreported.

How does yarrow work?

Yarrow contains various active compounds, such as apigenin and quercetin, which are known for their antioxidant, anti-inflammatory, and other beneficial effects that may support its traditional uses. However, more research is needed to fully understand the biological activity and bioavailability of these components when used together.

What are other names for Yarrow?
Note that Yarrow is also known as:
  • Achillea millefolium
  • Milfoil
  • Thousand leaf
  • Soldier's woundwort
  • Nose bleed plant
  • Devil's nettle
  • Sanguinary
  • Old-man's-pepper
  • Stenchgrass

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Update History
2023-09-26 00:30:02

A few new studies added

minor

We added some new meta-analyses on this topic to our database.

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Reviewed By

2023-08-31 14:48:56

FAQ and database update

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The FAQs and database were updated and expanded based on new literature.

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References
  1. ^Ali SI, Gopalakrishnan B, Venkatesalu VPharmacognosy, Phytochemistry and Pharmacological Properties of Achillea millefolium L.: A Review.Phytother Res.(2017-Aug)
  2. ^Moerman, Daniel ENative American Ethnobotany: A Database of Foods, Drugs, Dyes and Fibers of Native American Peoples, Derived from Plants
  3. ^Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani MA New mouthwash for Chemotherapy Induced Stomatitis.Nurs Midwifery Stud.(2014-Sep)
  4. ^Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani MEffect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial.Eur J Oncol Nurs.(2015-Jun)
  5. ^Hajhashemi M, Ghanbari Z, Movahedi M, Rafieian M, Keivani A, Haghollahi FThe effect of Achillea millefolium and Hypericum perforatum ointments on episiotomy wound healing in primiparous women.J Matern Fetal Neonatal Med.(2018-Jan)
  6. ^Jaffary F, Nilforoushzadeh MA, Tavakoli N, Zolfaghari B, Shahbazi FThe efficacy of Achilles millefolium topical gel along with intralesional injection of glucantime in the treatment of acute cutaneous leishmaniasis major.Adv Biomed Res.(2014)
  7. ^Firouzabadi M, Pourramezani N, Balvardi MComparing the Effects of Yarrow, Honey, and Breast Milk for Healing Nipple Fissure.Iran J Nurs Midwifery Res.(2020)
  8. ^Shapira MY, Raphaelovich Y, Gilad L, Or R, Dumb AJ, Ingber ATreatment of atopic dermatitis with herbal combination of Eleutherococcus, Achillea millefolium, and Lamium album has no advantage over placebo: a double blind, placebo-controlled, randomized trial.J Am Acad Dermatol.(2005-Apr)
  9. ^Popovych V, Koshel I, Malofiichuk A, Pyletska L, Semeniuk A, Filippova O, Orlovska RA randomized, open-label, multicenter, comparative study of therapeutic efficacy, safety and tolerability of BNO 1030 extract, containing marshmallow root, chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the treatment of acute non-bacterial tonsillitis in children aged 6 to 18 years.Am J Otolaryngol.(2019)
  10. ^Van der Weijden GA, Timmer CJ, Timmerman MF, Reijerse E, Mantel MS, van der Velden UThe effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis.J Clin Periodontol.(1998-May)
  11. ^Durić K, Kovčić Hadžiabdić S, Durić M, Nikšić H, Uzunović A, Džudžević Čančar HEfficacy and safety of three plant extracts based formulations of vagitories in the treatment of vaginitis: a randomized controlled trial.Med Glas (Zenica).(2021-Feb-01)
  12. ^Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani AThe effect of Achillea Millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial.Complement Ther Med.(2020-Aug)
  13. ^Kazemian A, Toghiani A, Shafiei K, Afshar H, Rafiei R, Memari M, Adibi PEvaluating the efficacy of mixture of , , and on severity of symptoms, anxiety, and depression in irritable bowel syndrome patients.J Res Med Sci.(2017)
  14. ^Jenabi E, Fereidoony BEffect of Achillea Millefolium on Relief of Primary Dysmenorrhea: A Double-Blind Randomized Clinical Trial.J Pediatr Adolesc Gynecol.(2015-Oct)
  15. ^Strzępek-Gomółka M, Gaweł-Bęben K, Kukula-Koch WSpecies as Sources of Active Phytochemicals for Dermatological and Cosmetic Applications.Oxid Med Cell Longev.(2021)
  16. ^Pelkonen O, Abass K, Wiesner JThujone and thujone-containing herbal medicinal and botanical products: toxicological assessment.Regul Toxicol Pharmacol.(2013-Feb)
  17. ^Saeidnia S, Gohari A, Mokhber-Dezfuli N, Kiuchi FA review on phytochemistry and medicinal properties of the genus Achillea.Daru.(2011)
  18. ^Demirel MA, Suntar I, Ilhan M, Keles H, Kupeli Akkol EExperimental endometriosis remission in rats treated with Achillea biebersteinii Afan.: histopathological evaluation and determination of cytokine levels.Eur J Obstet Gynecol Reprod Biol.(2014-Apr)
  19. ^Bina F, Daglia M, Santarcangelo C, Baeeri M, Abdollahi M, Nabavi SM, Tabarrai M, Rahimi RPhytochemical profiling and ameliorative effects of Achillea cretica L. on rat model of endometriosis.J Ethnopharmacol.(2020-May-23)
  20. ^Alomair MK, Alabduladheem LS, Almajed MA, Alobaid AA, Alkhalifah EAR, Younis NS, Mohamed MEEssential Oil Mitigates Peptic Ulcer in Rats through Nrf2/HO-1 Pathway.Molecules.(2022-Nov-15)
  21. ^Canan Karamenderes, Sebnem ApaydinAntispasmodic effect of Achillea nobilis L. subsp. sipylea (O. Schwarz) Bässler on the rat isolated duodenumJ Ethnopharmacol.(2003 Feb)
  22. ^Moradi MT, Rafieian-Koupaei M, Imani-Rastabi R, Nasiri J, Shahrani M, Rabiei Z, Alibabaei ZAntispasmodic effects of yarrow (Achillea millefolium L.) extract in the isolated ileum of rat.Afr J Tradit Complement Altern Med.(2013)
  23. ^Vahid S, Dashti-Khavidaki S, Ahmadi F, Amini M, Salehi Surmaghi MHEffect of herbal medicine achillea millefolium on plasma nitrite and nitrate levels in patients with chronic kidney disease: a preliminary study.Iran J Kidney Dis.(2012-Sep)
  24. ^Huseini HF, Alavian SM, Heshmat R, Heydari MR, Abolmaali KThe efficacy of Liv-52 on liver cirrhotic patients: a randomized, double-blind, placebo-controlled first approach.Phytomedicine.(2005-Sep)
  25. ^Foucré C, Schulz S, Stritter W, von Mackensen I, Luchte J, Ivaki P, Voss A, Ghadjar P, Seifert GRandomized Pilot Trial Using External Yarrow Liver Compress Applications With Metastatic Cancer Patients Suffering From Fatigue: Evaluation of Sympathetic Modulation by Heart Rate Variability Analysis.Integr Cancer Ther.(2022)
  26. ^Pirus Ghadjar, Wiebke Stritter, Irina von Mackensen, Felix Mehrhof, Clara Foucré, Vincent H Ehrhardt, Marcus Beck, Pimrapat Gebert, Goda Kalinauskaite, Jacqueline S Luchte, Carmen Stromberger, Volker Budach, Angelika Eggert, Georg SeifertExternal application of liver compresses to reduce fatigue in patients with metastatic cancer undergoing radiation therapy, a randomized clinical trialRadiat Oncol.(2021 Apr 19)
  27. ^Ayoobi F, Moghadam-Ahmadi A, Amiri H, Vakilian A, Heidari M, Farahmand H, Fathollahi MS, Fatemi I, Shafiei SA, Alahtavakoli M, Shamsizadeh AAchillea millefolium is beneficial as an add-on therapy in patients with multiple sclerosis: A randomized placebo-controlled clinical trial.Phytomedicine.(2019-Jan)
Examine Database References
  1. Dysmenorrhea Symptoms - Jenabi E, Fereidoony BEffect of Achillea Millefolium on Relief of Primary Dysmenorrhea: A Double-Blind Randomized Clinical Trial.J Pediatr Adolesc Gynecol.(2015-Oct)
  2. Wound Healing - Jaffary F, Nilforoushzadeh MA, Tavakoli N, Zolfaghari B, Shahbazi FThe efficacy of Achilles millefolium topical gel along with intralesional injection of glucantime in the treatment of acute cutaneous leishmaniasis major.Adv Biomed Res.(2014)
  3. Mucositis Symptoms - Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani MA New mouthwash for Chemotherapy Induced Stomatitis.Nurs Midwifery Stud.(2014-Sep)
  4. Mucositis Symptoms - Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani MEffect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial.Eur J Oncol Nurs.(2015-Jun)
  5. Nipple Cracks - Firouzabadi M, Pourramezani N, Balvardi MComparing the Effects of Yarrow, Honey, and Breast Milk for Healing Nipple Fissure.Iran J Nurs Midwifery Res.(2020)
  6. Itching - Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani AThe effect of Achillea Millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial.Complement Ther Med.(2020-Aug)
  7. Plasma Nitrate - Vahid S, Dashti-Khavidaki S, Ahmadi F, Amini M, Salehi Surmaghi MHEffect of herbal medicine achillea millefolium on plasma nitrite and nitrate levels in patients with chronic kidney disease: a preliminary study.Iran J Kidney Dis.(2012-Sep)
  8. Fatigue Symptoms - Pirus Ghadjar, Wiebke Stritter, Irina von Mackensen, Felix Mehrhof, Clara Foucré, Vincent H Ehrhardt, Marcus Beck, Pimrapat Gebert, Goda Kalinauskaite, Jacqueline S Luchte, Carmen Stromberger, Volker Budach, Angelika Eggert, Georg SeifertExternal application of liver compresses to reduce fatigue in patients with metastatic cancer undergoing radiation therapy, a randomized clinical trialRadiat Oncol.(2021 Apr 19)
  9. Pain - Hajhashemi M, Ghanbari Z, Movahedi M, Rafieian M, Keivani A, Haghollahi FThe effect of Achillea millefolium and Hypericum perforatum ointments on episiotomy wound healing in primiparous women.J Matern Fetal Neonatal Med.(2018-Jan)